A tragically underrated Southern Gothic style horror movie, The Skeleton Key (2005) has been given a bum reputation; a movie that is often overlooked movie within the horror genre, it’s actually worth watching at least once. Caroline Ellis (Kate Hudson) is a confident, yet sweet-natured hospice nurse living in New Orleans who grows frustrated with the general lack of compassion and care that her patients receive from the home at which she works. This frustration leads her to find a new opportunity wherein she becomes a live-in nurse for Ben Devereaux (John Hurt), an elderly man whose health has rapidly declined directly following a stroke. The wife, Violet (Gena Rowlands) seems reluctant to have Caroline there, insisting that she isn’t the right fit for the job.
After a discussion with the family estate lawyer, Luke (Peter Sarsgaard), Violet finally agrees that since no one else will take the job, she’ll just have to settle for Caroline. After moving in, it becomes evident that there are disturbing things going on within this neglected mansion in the Bayou. Caroline only becomes aware of these peculiarities after the mute, wheelchair-bound Ben is found trying to escape the house during a storm. She begins to explore the house and comes across strange artifacts in the attic, where she was told Ben had been when he had the stroke that left him partially paralyzed. Suspicions further rise after she learns of the house’s mysterious past from Violet—that it originally belonged to a family that had lynched two African American servants that had a hoodoo room in the attic where Ben supposedly had his stroke.
Violet tells Caroline that the house still belongs to them, insinuating that their ghosts punished her husband for going into their sacred space, but that she refuses to let anything happen to herself. Caroline seems to never fully trust what Violet has to say and decides to investigate further by going to an authentic hoodoo shop to see what it’s really all about and find out if it’s possible for someone to recover after they believe that they’ve been cursed. Her distrust of Violet leads her to perform her own secret hoodoo ritual to try to reverse the state that Ben is in—which results in Ben regaining some ability to speak, immediately asking Caroline to help him get away from Violet.
It becomes increasingly clear to Caroline that Violet has been performing hoodoo on Ben and her growing belief that hoodoo is real causes her to try to rescue Ben from Violet’s evil clutches. When she’s unable to flee with Ben, she’s caught by Luke and it’s revealed that he has been Violet’s accomplice all along. The culmination of the movie comes when Caroline is somehow able to call 9-1-1, then her friend, where she proclaims that the hoodoo is, “all real,” before the line is cut. She inadvertently traps herself inside of a magic circle where it’s made clear that Violet is actually the female servant Mama Cecile and shortly thereafter, she turns on the recording of the Conjure of Sacrifice, which effectively switches their bodies.
It turns out that Papa Justify had previously been inhabiting Ben’s body and had taken over Luke’s body and after switching bodies with Caroline, Mama Cecile force-feeds Caroline (now in Violet’s body) a potion which induces the paralytic state that Ben had been in. The whole thing had been a trick to get Caroline to believe in the power of hoodoo—because after all, you must believe in hoodoo for it to work on you. Once emergency services arrive in the morning it’s also revealed that Violet had left the house to Caroline so that Mama Cecile and Papa Justify could remain in the home and continue their body-swapping plot as long as they desired.